Juventus badly need to improve their Serie A form, so hope Jonathan David, Kenan Yildiz and Weston McKennie can inspire them against struggling Pisa.
It kicks off at the Allianz Juventus Stadium in Turin at 19.45 GMT (20.45 CET).
You can follow all the build-up and action as it happens from today’s Serie A games on the Liveblog.
The Bianconeri performances have impressed the fans, above all the refusal to give in when fighting back from disastrous situations, but the results are starting to worry them too.
Out of the Champions League and Coppa Italia, they came back from 3-1 down to grab a last-gasp 3-3 draw against Roma last week.
It means in Serie A they managed only two points in the last four rounds, and with Como winning earlier today, they risk falling well behind in the fight for Champions League qualification.
Today is Luciano Spalletti’s 67th birthday, so he is hoping for a win as a gift.
Dusan Vlahovic returned to training over the last few days after three months out, but is not available today, along with Emil Holm and Arek Milik.
Manuel Locatelli returns from suspension to bolster the midfield, while Federico Gatti starts after his last-gasp equaliser with Roma.
David leads the attack with support from Kenan Yildiz, Francisco Conceicao and unexpected goal hero McKennie, the USMNT star fresh from signing a new contract.
It was reported Michele Di Gregorio would return in goal after he was dropped for a couple of matches due to some remarkable howlers, but instead Mattia Perin keeps the gloves.
Pisa are rock bottom of the Serie A table and seemingly doomed to relegation along with Hellas Verona.
New coach Oscar Hiljemark has done little to turn the tide, as after his debut draw with Verona, there were three consecutive defeats to Milan, Fiorentina and Bologna.
The visitors are still without Simone Scuffet, Daniel Denoon, Isak Vural and Lorran, with Arturo Calabresi returning to the starting XI.
Former Juve players Juan Cuadrado and Samuel Iling-Junior are in the squad.
Stefano Moreo and January signing Rafiu Durosinmi lead the attack.
Juventus vs. Pisa line-ups
Juventus: Perin; Kalulu, Bremer, Gatti, Cambiaso; Locatelli, Thuram; Conceiçao, McKennie, Yildiz; David
Pisa: Nicolas; Calabresi, Caracciolo, Coppola; Leris, Aebischer, Hojholt, Marin, Angori; Moreo, Durosinmi
Player statistic
| 40' |  |
Marius Marin |
| 48' | |
Mehdi Léris | ||
| Andrea Cambiaso (Assist: Kenan Yıldız) |
 |
54' | ||
| Khéphren Thuram | |
65' | ||
| 70' | |
Antonio Caracciolo | ||
| Bremer | |
72' | ||
| Kenan Yıldız (Assist: Francisco Conceição) |
|
75' | ||
| Jeremie Boga (Assist: Manuel Locatelli) |
|
90+3' |
Match statistic
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